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In this section you will find interesting articles about complementary and alternative medicine, written by the foundation IOCOB

Forget about Evidence Based Medicine, listen first to the patients

It happens often that what patients perceive as most effective treatments, usually doctors see as  less important, and what doctors see as most important, based on our evidence based medicine, patients see as undesirable and less effective! Oeps! This is not just a blurp from a doctor of alternative medicine. These are data from a survey among hundreds of spinal cord injury patients, conducted by experts from a world famous institute, the Dutch Rudolf Magnus Institute of Neuroscience and Centre of Excellence for Rehabilitation Medicine, from the University Medical Centre in Utrecht.

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Back pain in dogs and palmitoylethanolamide

Back pain is common in both dogs and humans, and a new treatment without side effects based on the all natural painkiller palmitoylethanolamide  (PeaPure or a product which contains PEA) is now available. PeaPure is available via a webshop in Europe and produced in the Netherlands according to GMP; a product which contains PEA is available in Spain and Italy, and available in pharmacies. PeaPure is probably the best alternative for dogs, due to the absence of chemical fillers.

Back pain is often associated with intervertebral disc (IVD) degeneration.

Dr. Bergknut, N. wrote a PhD thesis on this topic, publihed in Acta Universitatis Agriculturae Sueciae, Volume: 2010, Issue: 91 (2011), from which we quote parts of the summary.

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Palmitoylethanolamide for horses suffering from chronic pain and/or inflammations

Horses often suffer from chronic pain states related to running, jumping or other movement- related disorders. Mostly either vetenarian analgesics or supplements are administered. The vetenarian analgesics have a clear drawback, namely various side effects, and most of the supplements are not scientifically well established as effective treatments.

Especially the use of corticosteroids and analgesics give rise to side effcts in horses wich can compromise their functions and quality of life.
The body own analgesic and anti inflammatory agent palmitoylethanolamide can be succesfully applied to horses and horses suffering chronic pain and/ or inflammation. Many studies in various animals have proven the efficacy and safety of palmitoylethanolamide. The compound also has relevant efficacy in horses, as we will demonstrate in the following cases.

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Pain and inflammation in horses: natural treatment

In nature animals have always been threatened by inflammation and pain. Inflammation and pain often go hand in hand. Often pain and inflammation are natural strategies of animals to survive: pain indicates and acts as an emergency signal, and inflammation kills bacteria and viruses.

However, there are types of pain and inflammation who are no good for survival. In man we know these states as auto-immune disorders, diseases such as rheumatoid artritis, inflammatory bowel disorder and the like.

In these cases the body itself attacks the tissues of the body itself, for no obvious reason at all. Inflammation without infection, without bacteria or viruses attacking our body we call aseptical inflammation. Chronic inflammation and pain are the base for a variety of disorders leading to unhappy horses. Some of these are: synovitis (inflammation joint membranes), artritis, tendinitis, colitis, skin hypersensitivity and eczema and many non-bacterial inflammations more.

Inflammation is a natural defence mechanism against tissue injury and usually leads to successful tissue healing. Sometimes, the inflammatory process itself actually causes further injury. In such circumstances it is appropriate to intervene with analgesic (pain-killing) and anti-inflammatory drugs. We will demonstrate the usefulness of a natural painkiller and anti-inflammatory compound, which is regarded as a breakthrough in the treatment of pain and inflammation.

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Palmitoiletanolamida es un nuevo tratamiento natural de dolor crónico!

Levi-Montalcini: Palmitoilethanolamida

Palmitoiletanolamida es un nuevo tratamiento natural de dolor crónico!

Rita Levi-Montalcini worked with Pure PEA

Rita Levi-Montalcini worked with Pure PEA

En 1993 descubrió y describió el premio Nobel de la Profesora Rita Levi-Montalcini funcionamiento del PEA. Ella también escribió que la PEA es una molécula natural muy importante.

Desde entonces, han pasado muchas cosas. Mientras tanto, miles de personas de todo el mundo utilizan a diario PEA. Para el dolor crónico y la inflamación crónica. El tejido es entonces docenas estudios investigaron un total de miles de pacientes. Está claramente demostrado ser eficaz y seguro.


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La cystite interstitielle ou de l’infection de la vessie et traitement




La cystite est un mot difficile pour une infection de la vessie. La
cystite interstitielle est plus compliquée. Il s’agit d’une inflammation
chronique de la vessie, où les bactéries ne jouent aucun rôle. On estime que
plusieurs milliers de personnes dans notre pays souffrent de cette méchante maladie
de la vessie, et la plupart d’entre eux sont des femmes. Avant de parler de la
cystite interstitielle, le médecin traitant, un urologue ou un gynécologue doit
être consulté afin d’exclure l’existence d’une infection ou un cancer. Ce sont
les deux conditions qui causent le plus de problèmes et de douleurs en urinant.

Parce que  «la cystite
interstitielle » est un terme difficile, nous utilisons plutôt le terme «syndrome
douloureux de la vessie ». Ce terme recouvre exactement la charge: c’est
douloureux, liés à la vessie et aucune maladie évidente mais un syndrome!

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Treating neuropathic pain: Congress Berlin 2010

Treatment of neuropathic pain, an overview presented at the 3rd European Congress for Integrative Medicine, in Berlin, December 3rd, 2010. The founding fathers of the Institute of Neuropathic pain in Soest (NL) attended the above mentioned congress to present the integrated treatment concept for neuropathic pain to an audience of physicians interested in pain treatment. The director of research and development from the institute, professor Jan M. Keppel Hesselink, presented the multimodal therapy as it has been developed within the institute over the past years.

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New hope for chronic pain patients: breakthrough


There is a new painkiller available in Germany and other European countries, based on a body own and all
natural compound which proved to be effective and without any troublesome
side effects, professor Jan M. Keppel Hesselink, pointed out at an
important medical congres in Italy on November 24-26, 2011. Leading international pain experts, such as the German professor Ralph Baron also spoke at that congres. 

Keppel hesselink, holding a chair in molecular pharmacologist at the
University of Witten/Herdecke in Germany, presented a major breakthrough in chronic
pain treatment during the anual neurological congress for Italian
anesthesiologists and painspecialists (SAARTI). While nearly all painkillers available
inhibit pain via the nerve cells, Keppel Hesselink pointed out that a
totally different and natural approach via the modulation of the so called glia cells
has been overseen. The compound is available as the foodsupplement PeaPure  and as a product which contains PEA .

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MS, chronische Schmerzen, Spasmen und die Behandlung mit körpereigenen Stoff Palmitoylethanolamid

Viele MS Patienten haben Schmerzen, Spasmen oder auch schmerzhafte Spasmen und würden gerne Cannabis zur Linderung gebrauchen. Allerdings lassen die Auswirkungen auf die Psyche und die aufwändigen Einnahmemöglichkeiten in Form von einem Joint oder Tee, die Patienten von diesem Gebrauch zurückschrecken. Doch jetzt wurde dank einer italienischen Nobelpreisträgerin ein körpereigener cannabisartiger Stoff entwickelt, ein sogenanntes Endocannabinoid. Dieses Mittel hat zum einen eine schmerzlindernde und zum anderen eine entzündungshemmende Wirkung, ohne dass dabei Auswirkungen auf die Psyche zu verzeichnen sind. Man wird hiervon nicht high, es wird einem nicht schwindelig und es tritt auch kein Zustand der Verwirrung auf. Es ist palmitoylethanolamid ( PeaPure).

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La question centrale dans le traitement de la douleur chronique avec a product which contains PEA®/PeaPure®

Alors que les analgésiques les plus populaires affectent seulement la membrane cellulaire (l’enveloppe de la cellule), ce qui signifie qu’ils bloquent l’échange de substances, a product which contains PEA@ ou PeaPure® va plus loin pénètre dans le noyau cellulair.  

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