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In this section you will find interesting articles about complementary and alternative medicine, written by the foundation IOCOB

Ozon therapy for Lyme: facts or church?

We analysed a debate on Facebook between a physician interested in complementary medicine (Dr) and a group called Ozon-wellness, supporting the use of ozone therapy in Lyme. The answers are from the Lyme group coordinator/moderator (L). Although the group was called Ozon Wellness, it basically was a group of patients interested in Lyme related to […]

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Achilles, a new non-rational nutraceutical containing palmitoylethanolamide

Palmitoylethanolamide (PEA) is a all natural painkiiller. It is quite hot and since 2008 Achilles is a new nutraceutical containing palmitoylethanolamide a number of different formulations of PEA has been entering the world wide market. PEA has been proven to be effective and safe in a great number of clinical trials

It all started with Normast 300 mg tablets, matrix tablets containing PEA and some excipients, Normast 600 mg matrix tablets and Normast 600 mg sachets, containing PEA and sorbitol. In all these formulations the amount of PEA in each capsule was around 60-65%. After Normast a pure product was introduced, containing PEA only, without any chemical excipient: PeaPure.

In parralel with Normast Pelvilen was introduced in Italy, as well as Adolene, both containing PEA and a herbal compound, a resveratrol, as well as Glialia, containing PEA with another herbal extract, luteolin.

For all these herbal additions clinical support was flimsy. Now a new herbal mix has been introduced, Achilles, containing in each tablet 100 mg PEA and the rest consists of various herbal extracts, Heteropterys Aphrodisiaca Extract: 250 mg , Cissus Quadrangularis Extract 250 mg , Zingiber Zerumbet Extract 150 mg and Siegesbeckia Orientalis Extract 75 mg. The clinical rationale is totally absent. 

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Informazioni per gli specialisti, i medici di base e i farmacisti: palmitoiletanolamide (PEA), un antidolorifico convalidato da EBM (evidence-based medicine), in vendita come PeaVera

Palmitoiletanolamide come antidolorifico PeaVera®: prodotto nei Paesi Bassi La palmitoiletanolamide (PEA) è disponibile in tutto il mondo dal 2012, come antidolorifico PeaVera. PeaVera viene prodotto nei Paesi Bassi, in uno stabilimento certificato GMP. La PEA viene testata per la purezza in un laboratorio americano indipendente. Il certificato di analisi può essere consultato sul sito Web del fornitore di […]

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Theanine: a useful and a supplement, generally recognized as safe (GRAS)

What kinds of
theanine do we get on the market?

There are two
sorts of supplements available on the market:

1. a synthetic form, mostly branded under the name Suntheanine and
consisting of  purified L-theanine which
is derived from chemical, enzymatic synthesis and

2. a pure natural form,
l-theanine, consisting of the natural aminoacid in tea leaves and produced by a
natural fermentation process of these tea leaves.

The subject
ingredient of tea leaves, the compound L-theanine, is an amino acid which is
also known under different names, 
y-glutamylethylamide or N-ethyl-L-glutamine.

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Amyotrofe laterale sclerose: palmitoylethanolamide

We kennen de poster allemaal. "Ik ben inmiddels overleden", zoiets schokkends staat erop. Het gaat dan om sprekende koppen van mensen die ALS hadden en reeds overleden zijn.

Amyotrofe laterale sclerose (voor het eerst beschreven door de grote neuroloog Charcot in 1869) is een vreselijk ziektebeeld, dat snel progressief is, met spierverval en spierkracht afname, waarbij alle spieren aangedaan kunnen zijn. Tot en met de ademhalingsspieren toe. Een goede behandeling is er in wezen nog steeds niet. Mensen sterven meestal binnen enkele jaren.

Daarom zijn de resultaten uit een Italiaans revalidatie-kliniek op Sardinie  zo indrukwekkend. Twee ALS patienten werden daar behandeld met de natuurlijke ontstekingsremmende en pijnstillende lichaamseigen stof palmitoylethanolamide (PEA), dat verkrijgbaar is als het supplement Normast. Positieve effecten waren vrijwel direct meetbaar.

Elders in de wereld zijn ALS patienten begonnen met het gebruik van PEA. Vooral patienten met de bulbaire vorm lijken relatief snel een positief effect te merken. Palmitoylethanolamide wordt door het lichaam zelf aangemaakt als reparatie molecuul bij ALS.

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PEA: informazioni palmitoilethanolamide

I neutraceutici PEA (PeaVera, Palmidrol, e altri PEA prodotti), sia palmitoiletanolamide antidolorifico naturale (PEA) contengono, aprendo la strada a un nuovo metodo naturale di trattamento del dolore cronico. Entrambi i prodotti sono realizzati secondo i più alti standard (GMP). Perché PEA nei Paesi Bassi solo dal 2010, e abbiamo anche molte domande per telefono, ecco un elenco di domande e risposte. Anche domande e commenti da parte di persone su Fori di discussione su PEA parlare, abbiamo elaborato.

Fine anno del 2012 nei Paesi Bassi, sono decine di migliaia di pazienti trattati con PEA. Non ci sono effetti collaterali significativi segnalati. PEA può essere senza problemi, oltre a prendere altri farmaci e medicinali.

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Pelvic Neuropathy by Pelvic Messenger

De invalshoek die we de laatste jaren ontwikkeld hebben, ‘iedereen heeft recht op pijnstilling zonder bijwerkingen’ krijgt ook in het buitenland steeds meer resonantie. De voorzitter van Stichting IOCOB was gast op een anderhalfuur durend interview over de behandeling van bekkenpijnen. De ‘show’ heet The Pelvic Messenger en werd door vele duizenden patienten beluisterd. Het interview is te horen op de link hieronder.

The Pelvic Messenger 

The show "The Pelvic Messenger" has been created as a live talk podcast which stems from the website PelvicMessenger. I, Jessica Mariotti Tomsic, have suffered from severe Chronic Neuropathic Pelvic Pain and multiple other co-morbidities.

My colleague, Elisabeth Oas, created this arena in which others can come and find resources, information and hope. It is our mission to help educate the patient on how to best get a complete diagnosis, more effective treatment, and eventually have a better quality of life. Please refer to for more info. You may also visit my blog at: for my personal story.

The guest is Prof. dr. Jan M. Keppel Hesselink, MD, MS, PhD, of the Institute for Neuropathic Pain in The Netherlands.

He will be discussing his strong interest in chronic pelvic pain and treatment modalities. I can assure my listeners they will always find something positive to inspire hope from this show. Knowing they are not alone and their is always a way in which to see better results, by addressing their own personal formula of success!!

Listen on:  

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Avoid magnesium stearate in supplements if possible

Magnesium stearate is widely used as an excipient in supplements, dietfood for medical purposes and drugs, because machines compressing tablets run more smooth if magnesium starate is added to tablets. Basically this thus has nothing to do with our body but all with the industriel proces of making tablets. We will give an example of two supplements, and bring arguments why one should chose the supplement devoid of magnesium stearate.


Magnesium stearate is the base of the Normast tablets, and many people have asked in the past why does Normast which contains the natural and body-own protective fatty compound palmitoylethanolamide, also contains such an unatural fat as magnesium stearate?

In the table both supplements are compared. Normast contains magnesium stearate and a number of other excipients which have no use of the organism, but are only put in based for pharmaceutical and technical reasons for instance, to be able to press tablets more quickly. Therefore the purity of palmitoylethanolamide in each tablet or capsule is 30% lower in Normast compared to PeaPure, which does not contain any excipients. But now the science why magnesium stearate is not such a good idea in foodsupplements.

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Glia modulation as a new key for analgesics

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Ueber PeaPure: wirksame Substanz, Palmitoylethanolamid

Normast ist seit November 2012 in den Niederlanden nicht mehr verfügbar. Normast in den Niederlanden wird durch PeaPure ersetzt.

Die Wirkung von Palmitoylethanolamid entfaltet sich durch natürliche Mechanismen des Körpers. Nach der Einnahme kommt es zu zahlreichen biologischen Prozessen in den Zellen. Dadurch kann es einige Wochen dauern, bevor die Wirkung spürbar ist.  

PeaPure ist nach neuesten wissenschaftlichen Erkenntnissen entwickelt.

PeaPure enthält Palmitoylethanolamid, wie Normast. PeaPure wurde aber keinerlei chemischer Hilfsstoff, Geschmacksstoff, Farbstoff oder Süßstoff zugefügt. 
Dem Inhalt Normast sachets enthalt Sorbitol. 
Es gibt Nutzer, die diesen Süßstoff nicht einnehmen möchten. 
PeaPure-Kapseln enthalten kein Sorbitol, einzig und allein Palmitoylethanolamid.

PeaPure nimmt man am besten während oder nach der Mahlzeit ein.
Es hat sich erwiesen, dass 3 Mal täglich 1 Kapsel à 400 mg eine gute Anfangsdosierung während der ersten 2 Monate ist.

Anwender van PeaPure spüren im Allgemeinen eine Verbesserung in den ersten Wochen der Einnahme. 
Erst nach zwei Monaten lässt sich die Wirkung von PeaPure wirklich beurteilen.

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