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Ioannides: a professor with Balls!

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Professor Ioannides is epidemiologist and internist and it is his belief that science and truth are not the same. In some controversial articles he worked from that vision. There is much to so-called bias in published articles. This is not least because a lot of research done, and because the hunt is often relatively small effects. There are too few studies duplicated, because the journals have a bias and prefer to publish original documents. Publications cover moreover but a very small part of the research, and in the non-visible part have a lot of errors.

Ioannidis appears with his criticism of the contemporary medical testing at Chalmers, that we have discussed on this website, as a result of his new book Testing Treatments.

We share his vision here integral weather:

There is increasing concern that most current published research findings are false.

The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field.

In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller, when there is a greater number and lesser preselection or tested relationships, where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice, and when more teams are involved in a scientific field in chase of statistical significance.

Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. Moreover, for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias.

Based on the insights of Ioannidis and Chalmers, we can say that there is no difference between mainstream and complementary medicine behandelvormen. In both sports are good (low) and less good (more) articles. The classification may actually complementary versus regular on the basis of research no longer made, but only on the basis of the fact that the complementary behandelvormen not taught at university. And even that is in the USA no longer true. Only in the Netherlands but still ….

We end with a quote of particular Ioannidis:

The truth is filed away somewhere. Meanwhile, most published research findings are false.

Ioannidis, a professor who dares!  And let his message and those of Chalmers used to come to better understanding of what facts are, and what truth is. The myth of the value science and medicine was already doorgeprikt, but Ioannidis Chalmers and give again a very nice contemporary image.

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